PhD Position (Translational Tumor Immunology)

PhD Position (Translational Tumor Immunology) 100%

Department Biomedizin

Das Universitätsspital Basel nimmt eine führende Rolle in der (inter-)nationalen Medizin- und Forschungslandschaft ein. Unser Campus im Herzen der Stadt Basel steht für Innovationskraft, Weiterentwicklungsmöglichkeiten und interdisziplinäre Zusammenarbeit.

available immediately (application deadline 15th November)
One year with option to extend
Petersgraben 4, 4031 Basel

Das können Sie bewegen

• Investigate endogenous anti-tumor T cell responses and epitope spreading following targeted cancer therapies
• Identify and experimentally validate patient-specific tumor antigens and T cell epitopes using genomic, computational and functional approaches
• Characterize tumor-reactive T cells longitudinally using functional assays, peptide–MHC tetramers, high-parameter flow cytometry and single-cell RNA/TCR sequencing
• Integrate immunological, molecular and clinical data to understand determinants of durable tumor control
• Take an active role in shaping the project, analyzing and presenting your data, and communicating the results through conferences and scientific publications

Das bringen Sie mit

• Master's degree in biological sciences, immunology, molecular biology, biomedical sciences, medicine or a related field
• Hands-on experience in experimental laboratory research and a strong interest in T cell immunology, cancer immunotherapy and translational human research
• Interest in quantitative biology and willingness to work with complex genomic, single-cell and immunological datasets
• Scientific curiosity, initiative and the ability to work independently while contributing effectively to an interdisciplinary team
• Excellent English communication and writing skills; experience with primary human samples, flow cytometry, T cell assays, molecular biology, sequencing, bioinformatics, R or Python is an advantage

Benefits dieser Stelle

• Access to state-of-the-art infrastructure for flow cytometry, DNA and RNA sequencing, cell culture and high-dimensional data analysis
• Direct access to longitudinal clinical samples from patients undergoing advanced cancer therapies
• A highly interdisciplinary environment connecting experimental immunology, translational oncology and clinical research
• Close collaboration with basic and clinical research groups at the Department of Biomedicine, University Hospital Basel and external partner institutions
• Cross-disciplinary training opportunities in human immunology, cancer biology, genomics and computational data analysis
• The opportunity to contribute to a broader research program investigating endogenous anti-tumor immunity across cancer types and therapeutic modalities

Weitere Auskünfte

Christoph Schultheiss
DBM Projektleiter
+41 61 265 35 33

Sarah Bass
HR Berater/in
+41 61 265 32 90