Unispital Basel

PhD Position (Translational Tumor Immunology) 100 % Department Biomedizin PhD Position (Translational Tumor Immunology) 100 % Department Biomedizin

Schweiz · Department Biomedizin

Arbeitszeit Vollzeit Befristung befristet 1 Jahr

PhD Position (Translational Tumor Immunology) 100%

Department Biomedizin
Universitätsspital Basel (USB)

Das Universitätsspital Basel nimmt eine führende Rolle in der (inter-)nationalen Medizin- und Forschungslandschaft ein. Unser Campus im Herzen der Stadt Basel steht für Innovationskraft, Weiterentwicklungsmöglichkeiten und interdisziplinäre Zusammenarbeit.

Anstellungsbeginn / Frist: 01.01.2027 (application deadline 15th November)
Dauer: One year with option to extend
Arbeitsort: Petersgraben 4, 4031 Basel

Das können Sie bewegen

Investigate mechanisms of response and resistance to immune checkpoint blockade in solid tumors, with a focus on head and neck and esophagogastric cancers
Characterize the tumor immune microenvironment using spatial proteomics, multiplex imaging and spatial transcriptomics
Integrate tissue-based immune profiles with blood-based biomarkers, immune repertoires and clinical outcomes to identify markers for patient stratification and treatment response
Establish patient-derived 3D tumor models and explants and perform functional tumor–immune cell experiments to validate resistance mechanisms and therapeutic strategies
Take an active role in planning and conducting the project, analysing complex datasets, collaborating with clinical and scientific partners, and presenting and publishing your findings

Das bringen Sie mit

Master's degree in biology, biomedical sciences, biochemistry, molecular medicine, immunology, cancer biology or a related life-science discipline
Strong interest in translational cancer research, tumor immunology and modern spatial profiling technologies
Solid hands-on experience in mammalian cell culture and molecular or cellular biology, ideally in the context of tumor biology
Initiative, scientific curiosity and the ability to work independently and collaboratively in an interdisciplinary and international environment
Excellent English language skills; experience with primary human samples, flow cytometry, spatial technologies, 3D models, functional assays or quantitative data analysis using R/Python is an advantage

Benefits dieser Stelle

Work at the interface of experimental tumor immunology, clinical research and patient care
Access to state-of-the-art technologies and infrastructure for spatial profiling, flow cytometry, sequencing and functional tumor models
Close collaboration with physicians, bioinformaticians and basic and translational research groups
Cross-disciplinary training and substantial opportunities for scientific development, independence and project ownership